RESEARCH PUBLICATIONS
RESEARCH PROJECT LIST:-
CHIKUNGUNYA
Development of serological assay for detection of Chikungunya virus infection. (2016 - 2018)
- Dr Magdline Sia Henry Sum
Gene Expression Profiling Analysis Of Dengue Virus And Chikungunya Virus Infection. (2012 - 2015)
- Dr Magdline Sia Henry Sum
Expression and evaluation of a 24-kDa recombinant protein of the N-terminal E2 glycoprotein of chikungunya virus. (2015)
- Sum, M.S.H and Andrew, A. (pdf)
Expression of recombinant E1 glycoprotein of chikungunya virus in baculovirus expression system. (2015)
- Sum, M.S.H., Andrew, A. and Maling, M.A. (pdf)
Expression of N-terminal E2 glycoprotein of chikungunya virus for serological assay.
- Sum, M.S.H., & Andrew, A.
Early clearance of Chikungunya virus in children is associated with a strong innate immune response. (2016)
- Simarmata, D., Ng, D. C. E., Kam, Y. -., Lee, B., Sum, M. S. H., Her, Z., . . . Ng, L. F. P.
The reactivity of recombinant Chikungunya virus E2 protein under reduced and non-reduced conditions. (2017)
- Anna Andrew, Nur Aimi Aizah and Magdline Sia Henry Sum.
RESPIRATORY DISEASE
A prospective study on the epidemiology of severe community-acquired lower respiratory tract infection in children aged 5 years and below in Sarawak. (2012 - 2015)
- Professor Dr David Perera
DENGUE
Differential Expression of cellular proteins in response to dengue, Chikungunya, Zika and Japanese encephalitis infections: Prognosis of potential biomarkers (2017 - 2021)
- Dr Magdline Sia Henry Sum
Gene Expression Profiling Analysis Of Dengue Virus And Chikungunya Virus Infection. (2012 - 2015)
- Dr Magdline Sia Henry Sum
Mechanism and Public Health Impact of Sylvatic Dengue emergence in Borneo. (2016 - 2018)
- Professor Dr David Perera
The emergence of a new dengue serotype in South east Asia. (UTMB Project)
- Professor Dr David Perera
Serotype-specific host responses in rhesus macaques after primary dengue challenge. (2013)
- Hickey AC, Koster JA, Thalmann CM, Hardcastle K, Tio PH, Cardosa MJ, Bossart KN (pdf)
Sylvatic dengue viruses share the pathogenic potential of urban/endemic dengue viruses. (2010)
- Vasilakis N, Cardosa J, Diallo M, Sall AA, Holmes EC, Hanley KA, Weaver SC, Mota J, Rico-Hesse R (pdf)
Emergence of the Asian 1 genotype of dengue virus serotype 2 in Viet Nam: in vivo fitness advantage and lineage replacement in South-East Asia. (2010)
- Vu TT, Holmes EC, Duong V, Nguyen TQ, Tran TH, Quail M, Churcher C, Parkhill J, Cardosa J, Farrar J, Wills B, Lennon NJ, Birren BW, Buchy P, Henn NR, Simmons CP (pdf)
Viremia and the Magnitude of the Immune Response upon Infection of Green Monkeys with Dengue Virus Type 2 Are Strain-Dependent. (2009)
- Martín J, Hermida L, Castro J, Romero Y, Cardosa J, Guillén G (pdf)
Importation and co-circulation of multiple serotypes of dengue virus in Sarawak, Malaysia. (2009)
- Holmes EC, Tio PH, Perera D, Muhi J, Cardosa J (pdf)
Dengue virus serotype 2 from a sylvatic lineage isolated from a patient with dengue hemorrhagic fever. (2009)
- Cardosa J, Ooi MH, Tio PH, Perera D, Holmes EC, Bibi K, Abdul Manap Z (pdf)
Dengue virus serotype 2 from a sylvatic lineage isolated from a patient with dengue hemorrhagic fever. (2009)
- Cardosa J, Ooi MH, Tio PH, Perera D, Holmes EC, Bibi K, Abdul Manap Z (pdf)
Viremia and antibody response in green monkeys (Chlorocebus aethiops sabaeus) infected with denguevirus type 2: a potential model for vaccine testing. (2009)
- Martín J, Hermida L, Castro J, Lazo L, Martínez R, Gil L, Romero Y, Puente P, Zaragoza S, Cosme K, Guzmán MG, Cardosa J, Guillén G (pdf)
Phylogeny of dengue viruses circulating in Jeddah, Saudi Arabia: 1994 to 2006. (2008)
- Zaki A, Perera D, Jahan SS, Cardosa MJ (pdf)
Scientific consultation on immunological correlates of protection induced by dengue vaccines: Report from a meeting held at the World Health Organisation, 17-18 November 2005. (2007)
- Hombach J, Cardosa MJ, Sabchareon A, Vaughn DW, Barrett AD (pdf)
Of cascades and perfect storms: The immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS). (2007)
- Pang T, Cardosa MJ, Guzman MG (pdf)
Two dimensional gel electrophoresis VOPBA reveals laminin receptor (LAMR1) interaction with dengue virus serotypes 1, 2 and 3. (2005)
- Tio PH, Jong WW, Cardosa MJ (pdf)
Antibodies Against prM Protein Distinguishes Between Previous Infection with Dengue and Japanese Encephalitis Viruses. (2002)
- Cardosa MJ, Wang SM, Sum MSH, Tio PH (pdf)
Dengue haemorrhagic fever: Questions of pathogenesis. Current Opinion in Infectious Diseases. (2000)
- Cardosa MJ (pdf)
Dengue Vaccine Design: Issues and Challenges. (1998)
- Cardosa, MJ (pdf)
Pathophsyiologic and prognostic role of cytokines in dengue haemorrhagic fever. (1998)
- Bethell DB, Flobbe K, Phuong CXT, Day NPJ, Phuong PT, Buurman WA, Cardosa MJ, White NJ, Kwiatkowski D (pdf)
Possible occurrence of a genetic bottleneck occurred in dengue serotype 2 viruses between the 1980 and 1987 epidemic seasons in Thailand. (1997)
- Sittisombut N, Sistayanarain A, Cardosa MJ, Salminen M, Damrongdachakul, Kalayanarooj S, Rojanasuphot S, Supawadee J, Maneekarn N (pdf)
MELIOIDOSIS
Investigating the relationship between Micromonospora genus and Burkholderia pseudomallei in melioidosis-endemic region of Sarawak through metagenomic approaches. (2020 - 2022)
- Dr Yuwana Podin
Biogeography of Burkholderia pseudomallei in Malaysian Borneo States of Sabah & Sarawak. (2017 - 2019)
- Dr Yuwana Podin
Molecular Characterization of Clinical and Environmental Burkholderia pseudomallei Strains From Sarawak. (2016 - 2018)
- Dr Yuwana Podin
Genomic Characterization of Burholderia pseudomallei from Sabah and Sarawak. (2015 - 2018)
- Dr Yuwana Podin
Investigation of B. pseudomallei in soil and water samples melioidosis hyper-endemic regions in Kapit, Sarawak. (2014 - 2015)
- Dr Yuwana Podin
Reliability of automated biochemical identification of Burkholderia pseudomallei is regionally dependent. (2013)
- Podin Y, Kaestli M, McMahon N, Hennessy J, Ngian HU, Wong JS, Mohana A, Wong SC, William T, Mayo M, Baird RW, Currie BJ (pdf)
Burkholderia pseudomallei Isolates from Sarawak, Malaysian Borneo, Are Predominantly Susceptible to Aminoglycosides and Macrolides. (2013)
- Podin Y, Sarovich DS, Price EP, Kaestli M, Mayo M, Hii K, Ngian H, Wong S, Wong I, Wong J, Mohan A, Ooi M, Fam T, Wong J, Tuanyok A, Keim P, Giffard PM, Currie BJ (pdf)
HAND, FOOT AND MOUTH DISEASE (HFMD)
Adenovirus-21 Associated Acute Flaccid Paralysis During A Hand, Foot and Mouth Disease Outbreak in Sarawak, Malaysia. (2003)
- Ooi MH, Wong SC, Clear D, Perera D, Krishnan S, Preston T, Tio PH, Willison HJ, Tedman B, Kneen R, Cardosa MJ, Solomon T (pdf)
Epidemiological and virologic investigation of hand, foot and mouth disease in Southern Vietnam. (2007)
- Tu PV, Thao NTT, Perera D, Huu TK, Tien NTK, Thuong TC, Ooi MH, Cardosa MJ, McMinn PC (pdf)
Evaluation of different clinical sample types in the diagnosis of human enterovirus 71 associated hand, foot and mouth disease. (2007)
- Ooi MH, Solomon T, Podin Y, Mohan A, Akin W, Yusuf MA, del Sel S, Mohd Kontol K, Lai BF, Clear D, Chieng CH, Blake E, Perera D, Wong SC, Cardosa MJ (pdf)
Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. (1999)
- Cardosa MJ, Krishnan S, Tio PH, Perera D, Wong SC (pdf)
Validation and utilization of an internally controlled multiplex Real-time RT-PCR assay for simultaneous detection of enteroviruses and enterovirus A71 associated with hand foot and mouth disease. (2015)
- Tran Tan Thanh, Nguyen To Anh, Nguyen Thi Tham, Hoang Minh Tu Van, Saraswathy Sabanathan, Phan Tu Qui, Tran Thuy Ngan, Tran Thi My Van, Lam Anh Nguyet, Nguyen Thi Han Ny, Le Thi My Thanh, Ong Kien Chai, David Perera, Do Chau Viet, Truong Huu Khanh, Do Quang Ha, HaManh Tuan, Kum Thong Wong, Nguyen Thanh Hung, Nguyen Van Vinh Chau, Guy Thwaites, H Rogier van Doorn and Le Van Tan (PDF)
RABIES
Develop New Rabies Diagnostics for On-Site Testing At Sarawak Hospitals and Source Origins of Rabies Virus In Sarawak. (In Process/Active)
- Professor Dr David Perera
Digitising the rabies outbreak in Sarawak: An approach to generating diagnostic assays and mathematical modelling to predict disease transmission. (2018 - 2020)
- Professor Dr David Perera
CORONAVIRUS DISEASE
Projek Khas Pengendalian Kes Coronavirus Disease 2019 (COVID-19). (2020 - 2021)
- Professor Dr David Perera
Saringan Covid-19: Projek Khas Makmal Diagnostik (Kerjasama Strategik KPT-MOSTI). (2020 - 2021)
- Professor Dr David Perera
Determination and application of immunodominant regions of SARS coronavirus spike and nucleocapsid proteins recognized by sera from different animal species. (2008)
- Yu M, Stevens V, Berry JD, Crameri G, McEachern J, Tu C, Shi Z, Liang G, Weingartl H, Cardosa J, Eaton BT, Wang LF (pdf)
JAPANESE ENCEPHALITIS (JE)
The Involvement of Microtubules and Actin during the Infection of Japanese Encephalitis Virus in Neuroblastoma Cell Line, IMR32. (2015)
- Sum, M.S.H. (pdf)
The effect of vaccination coverage and climate on Japanese encephalitis in Sarawak, Malaysia. (2013)
- Impoinvil DE, Ooi MH, Diggle PJ, Caminade C, Cardosa MJ, Morse AP, Baylis M, Solomon T (pdf)
Evaluation of two commercially available ELISAs for the diagnosis of Japanese encephalitis applied to field samples. (2010)
- Lewthwaite P, Veera Shankar M, Tio PH, Daly J, Last A, Ravikumar R, Desai A, Ravi V, Cardosa J, Solomon T (pdf)
The epidemiology, clinical features, and long-term prognosis of Japanese encephalitis in central Sarawak, Malaysia. (2008)
- Ooi MH, Lewthwaite P, Lai BF, Mohan A, Clear D, Lim L, Krishnan S, Preston T, Chieng CH, Tio PH, Wong SC, Cardosa J, Solomon T (pdf)
A decade of Japanese encephalitis surveillance in Sarawak, Malaysia. (2008)
- Wong SC, Ooi MH, Abdullah AR, Wong SY, Krishnan S, Tio PH, Pek PC, Lai BF, Mohan A, Muhi J, Kiyu A, Arif MT, Cardosa MJ (pdf)
A cohort study to assess the new WHO Japanese encephalitis surveillance standards. (2008)
- Solomon T, Thao TT, Lewthwaite P, Ooi MH, Kneen R, Dung NM, White N (pdf)
A decade of Japanese encephalitis surveillance in Sarawak, Malaysia:1997-2006. (2007)
- Cardosa MJ, Wong SC, Ooi MH, Abdullah AR, Wong SY, Krishnan S, Tio PH, Pek PC, Lai BF, Mohan A, Muhi J, Kiyu A, Arif MT (pdf)
Origin and evolution of Japanese encephalitis virus in Southeast Asia. (2003)
- Solomon T, Ni H, Beasley DWC, Ekkelenkamp M, Cardosa MJ, Barrett ADT (pdf)
Antibodies Against prM Protein Distinguishes Between Previous Infection with Dengue and Japanese Encephalitis Viruses. (2002)
- Cardosa MJ, Wang SM, Sum MSH, Tio PH (pdf)
Rapid diagnosis of Japanese encephalitis by using an immunoglobulin M dot enzyme immunoassay. (1998)
- Solomon T, Le TTT, Nguyen MD, Kneen R, Nguyen TH, Nisalak A, Vaughn DW, Farrar J, Tran TH, White NJ, Cardosa MJ (pdf)
Carbon nanoparticle modified screen printed carbon electrode as a disposable electrochemical immunosensor strip for the detection of Japanese encephalitis virus. (2017)
- Fun Chin S., Shan Lim L., Cem Pang S., Henry Sum M. and Perera D.
A Novel Silver Nanoparticles-based Sensing Probe for the Detection of Japanese Encephalitis Virus Antigen. (2017)
- Lim LS, Chin SF, Pang SC, Henry Sum MS, Perera D
Carbon Nanoparticles Based Electrochemical Biosensor Strip for Detection of Japanese Encephalitis Virus. (2017)
- Lai HC, Chin SF, Pang SC, Magdline SHS, David P
Electrochemical Determination of Japanese Encephalitis Virus Antigen Using Silver Nanoparticles Modified Screen-Printed Carbon Electrode. (2019)
- Suk Fun Chin, Lih Shan Lim, Huat Choi Lai, Suh Cem Pang, Magdline Sia Henry Sum, and David Perera
RICE TUNGRO VIRUS
Over expression of Recombinant CP3 Protein of Rice Tungro Spherical Virus in Prokaryotic Expression System. (2014)
- Yee, S.F., Chu, C.H. and Sum, M.S.H. (pdf)
Development of a Dot-ELISA for Detection of Rice Tungro Disease. (2016 - 2018)
- Dr Magdline Sia Henry Sum
Vertical flow interaction of antigenic recombinant coat proteins against the affinity purified antibody of tungro viruses. (In Process)
- Dr Magdline Sia Henry Sum
Expression and the antigenicity of recombinant coat proteins of tungro viruses expressed in Escherichia coli. (2017)
- Yee S.F., Chu C.H., Poili E. and Sum M.S.H.
Development of an Indirect ELISA and Dot-Blot Assay for Serological Detection of Rice Tungro Disease. (2017)
- Sum, M.S.H., Yee, S.F., Eng, L., Poili, E., & Lambdin, J.
MALARIA
Lansium Domesticum: Skin and Leaf extracts of this fruit tree interrupt the lifecycle of Plasmodium falcipanum, and are active towards a chloroquine resistant strain of the parasite (T9) in vitro. (2003)
- Yapp DTT, Yap ST (pdf)
The isolation and structural characterization of n-Methyl-4-hydroxyproline from the fruit skin of Lansium spp. Cryst. Acta E. (2002)
- Yapp DT, Steed J, Yap SY, Houghton PJ (pdf)
ENTEROVIRUS
In enterovirus 71 encephalitis with cardio-respiratory compromise, elevated interleukin 1, interleukin 1 receptor antagonist, and granulocyte colony-stimulating factor levels are markers of poor prognosis. (2012)
- Griffiths MJ, Ooi MH, Wong SC, Mohan A, Podin Y, Perera D, Chieng CH, Tio PH, Cardosa MJ, Solomon T (pdf)
Enterovirus 71 encephalomyelitis and Japanese encephalitis can be distinguished by topographic distribution of inflammation and specific intraneuronal detection of viral antigen and RNA. (2012)
- Wong KT, Ng KY, Ong KC, Ng WF, Shankar SK, Mahadevan A, Radotra B, Su IJ, Lau G, Ling AE, Chan KP, Macorelles P, Vallet S, Cardosa MJ, Desai A, Ravi V, Nagata N, Shimizu H, Takasaki T (pdf)
Novel multiplex oligonucleotide-conjugated bead suspension array for rapid identification of enterovirus 71 sub genogroups. (2011)
- Wu Y, Tan EL, Yeo A, Chan KP, Nishimura H, Cardosa MJ, Poh CL, Quak SH, Chow VT (pdf)
A comparison of the VP1, VP2 and VP4 regions for molecular typing of human enteroviruses. (2010)
- Perera D, Shimizu H, Yoshida H, Tu PV, McMinn PC, Ishiko H, Cardosa MJ (pdf)
Formaldehyde-inactivated whole-virus vaccine protects a murine model of enterovirus 71 encephalomyelitis against disease. (2010)
- Ong KC, Devi S, Cardosa MJ, Wong KT (pdf)
Evolutionary dynamics and temporal/geographical correlates of recombination in the human enteroviruses, echovirus 9, 11 and 30. (2010)
- McWilliam Leitch EC, Cabrerizo M, Cardosa J, Harvala H, Ivanova OE, Kroes AC, Lukashev A, Muir P, Odoom J, Roivainen M, Susi P, Trallero G, Evans DJ, Simmonds P (pdf)
Virology, epidemiology, pathogenesis and control of enterovirus 71. (2010)
Solomon T, Lewthwaite P, Perera D, Cardosa MJ, McMinn P, Ooi MH (pdf)
Clinical features, diagnosis and management of enterovirus 71. (2010)
- Ooi MH, Wong SC, Lewthwaite P, Cardosa MJ, Solomon T (pdf)
Development of a multiplex polymerase chain reaction for simultaneous identification of human enterovirus 71 and coxsackievirus A16. (2010)
- Thao NT, Ngoc NT, Tu PV, Thuy TT, Cardosa MJ, McMinn PC, Phuektes P (pdf)
Enterovirus 75 encephalitis in children, Southern India. (2010)
- Lewthwaite P, Perera D, Ooi MH, Last A, Kumar R, Desai A, Begum A, Ravi V, Shankar MV, Tio PH, Cardosa MJ, Solomon T (pdf)
Formaldehyde-inactivated whole-virus vaccine protects a murine model of enterovirus 71 encephalomyelitis against disease. (2010)
- Ong KC, Devi S, Cardosa MJ, Wong KT (pdf)
Transmission networks and population turnover of echovirus 30. (2009)
- McWilliam Leitch EC, Bendig J, Cabrerizo M, Cardosa J, Hyypiä T, Ivanova OE, Kelly A, Kroes AC, Lukashev A, MacAdam A, McMinn P, Roivainen M, Trallero G, Evans DJ, Simmonds P. (pdf)
Pathologic characterization of a murine model of human enterovirus 71 encephalomyelitis. (2008)
- Ong KC, Badmanathan M, Devi S, Leong KL, Cardosa MJ, Wong KT (pdf)
Human enterovirus 71 disease in Sarawak, Malaysia – a prospective clinical, virological and molecular epidemiological study. (2007)
- Ooi MH, Wong SC, Podin Y, Akin W, del Sel S, Mohan A, Chieng CH, Perera D, Clear D, Wong D, Blake E, Cardosa MJ, Solomon T (pdf)
High titred neutralizing antibodies to human enterovirus 71 preferentially bind to the N terminal portion of the capsid protein VP1. (2007)
- Tan CS, Cardosa MJ (pdf)
Molecular phylogeny of modern Coxsackievirus A16. (2007)
- Perera D, Yusuf MA, Podin Y, Ooi MH, Thao NTT, Wong KK, Zaki A, Chua KB, Abdul Malik Y, Tu PV, Tien NTK, Puthavathana P, McMinn PC, Cardosa MJ (pdf)
Recombinant Newcastle Disease Virus capsids displaying enterovirus 71 VP1 fragment induce a strong immune response in rabbits. (2006)
- Sivasamugham LA, Cardosa MJ, Tan CS, Yusoff K (pdf)
Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: Lessons from the first 7 years. (2006)
- Podin Y, Gias ELM, Ong F, Leong Y-W, Yee S-F, Yusuf MA, Perera D, Teo B, Wee T-Y, Yao S-C, Yao S-K, Kiyu A, Arif MT, Cardosa MJ (pdf)
Review on flavivirus vaccine development. Proceedings of a meeting jointly organized by World Health Organization and the Thai Ministry of Public Health. (2005)
- Hombach J, Barret AD, Cardosa MJ, Deubel V, Guzman M, Kurane I, Roehrig JT, Sabchareon A, Kieny MP (pdf)
Incorrect identification of recent Asian strains of Coxsackievirus A16 as human enterovirus 71: improved primers for the specific detection of human enterovirus 71 by RT PCR. (2004)
- Perera D, Podin Y, Akin W, Tan CS, Cardosa MJ (pdf)
Molecular epidemiology of human enterovirus 71 strains associated with recent outbreaks in the Asia-Pacific Region: Comparative analysis based on the VP1 and VP4 genes. (2003)
- Cardosa MJ, Perera D, Brown BA, Cheon D, Chan HM, Chan KP, Cho H, McMinn P (pdf)
Phylogenetic analysis of Enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia. (2001)
- McMinn P, Lindsay K, Perera D, Chan HM, Chan KP, Cardosa MJ (pdf)
Late presentation of the Nipah virus encephalitis and kinetics of the humoral immune response. (2001)
- Wong SC., Ooi MH, Wong MN, Tio PH, Solomon T, Cardosa MJ (pdf)
Emerging Arboviral encephalitis (2000)
- Solomon T, Cardosa MJ (pdf)
Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. (1999)
- Cardosa MJ, Krishnan S, Tio PH, Perera D, Wong SC (pdf)
Disability after encephalitis: development and validation of a new outcome score. (2010)
- Lewthwaite P, Begum A, Ooi MH, Faragher B, Lai BF, Sandaradura I, Mohan A, Mandhan G, Meharwade P, Subhashini S, Abhishek G, Begum A, Penkulinti S, Shankar MV, Ravikumar R, Young C, Cardosa MJ, Ravi V, Wong SC, Kneen R, Solomon T (pdf)
